Search Results - deb+chatterjee

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Method for Targeted Therapeutic Delivery of Proteins into Cells

Abstract: Current methods to deliver proteins into cells (e.g., using retrovirus, DNA transfection, protein transduction, microinjection, complexing the protein with lipids, etc.) have many shortcomings, such as lack of target specificity toxicity, or unwanted random integration into the host chromosome. Protein transduction is an emerging technology...

Published: 4/8/2024 | Inventor(s): Deb Chatterjee, Stanislaw Kaczmarczyk

Keywords(s): virus-like particles, VLP

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices

Virus-Like Particles That Can Deliver Proteins and RNA

Abstract: The National Cancer Institute's Protein Expression Laboratory seeks parties interested in licensing the novel delivery of RNA to mammalian cells using virus-like particles. Current methods of delivering proteins or RNA to mammalian cells are limited by a lack of target specificity and toxicity, among other shortcomings. NCI researchers have...

Published: 4/8/2024 | Inventor(s): Stanislaw Kaczmarczyk, Deb Chatterjee

Keywords(s): antibody synthesis, Protein Expression, RNA delivery, virus-like particles

Category(s): Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease

Cancer Immunotherapy Using Virus-like Particles

Abstract: One major challenge in the development of effective cancer therapies is a lack of universal, cancer specific markers in target cells. The current standard therapies rely on surgery, chemotherapy, and radiation therapy. Such procedures lead to a population of resistant cancer cells that makes further applications of chemotherapy/radiation therapy...

Published: 4/8/2024 | Inventor(s): Stanislaw Kaczmarczyk, Deb Chatterjee

Keywords(s): virus-like particle, VLP

Category(s): TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing