Search Results - vlp

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Method for Targeted Therapeutic Delivery of Proteins into Cells

Abstract: Current methods to deliver proteins into cells (e.g., using retrovirus, DNA transfection, protein transduction, microinjection, complexing the protein with lipids, etc.) have many shortcomings, such as lack of target specificity toxicity, or unwanted random integration into the host chromosome. Protein transduction is an emerging technology...

Published: 4/8/2024 | Inventor(s): Deb Chatterjee, Stanislaw Kaczmarczyk

Keywords(s): virus-like particles, VLP

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices

Cancer Immunotherapy Using Virus-like Particles

Abstract: One major challenge in the development of effective cancer therapies is a lack of universal, cancer specific markers in target cells. The current standard therapies rely on surgery, chemotherapy, and radiation therapy. Such procedures lead to a population of resistant cancer cells that makes further applications of chemotherapy/radiation therapy...

Published: 4/8/2024 | Inventor(s): Stanislaw Kaczmarczyk, Deb Chatterjee

Keywords(s): virus-like particle, VLP

Category(s): TherapeuticArea > Oncology, Application > Therapeutics, Collaboration Sought > Licensing

Zika Virus VLP (Virus-like Particle) Antigens for Vaccine Candidate and Diagnostic Development

Zika virus (ZIKV) is a flavivirus primarily transmitted by infected Aedes mosquitoes. Infection with ZIKV during pregnancy can affect the fetus causing microcephaly, neurological complications, and other birth defects. Adults are also at a heightened risk of developing Guillain-Barre syndrome and other neurological disorders. In response to the 2015-2016...

Published: 7/25/2024 | Inventor(s): Brent Davis, Gwong-Jen Chang

Keywords(s): antibodies, ANTIGENS, NCEZID-DVBD, Vaccine, virus, VLP, Zika

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Zika Virus Vaccines

Zika virus (ZIKV) is a flavivirus transmitted by mosquitos that is strongly linked to neurological complications including Guillain-Barré syndrome, meningoencephalitis, and microcephaly. The association between active ZIKV infection during pregnancy and microcephaly and intrauterine growth retardation in the fetus has been confirmed in murine models...

Published: 7/25/2024 | Inventor(s): John Mascola, Wing-pui Kong, Eun Yang, Wei Shi, Theodore Pierson, Leda Castilho, Kimberly Dowd, Lingshu Wang, Christina Demaso, Rebecca Pelc, Adrian Creanga, Julie Ledgerwood, Sebastian Ramesch, Barney Graham

Keywords(s): Chimera, DC5BXX, GENE-BASED, JAPANESE ENCEPHALITIS VIRUS, vaccines, virus-like particles, VLP, Zika

Category(s): Collaboration Sought > Licensing, Application > Vaccines, TherapeuticArea > Infectious Disease