Search Results - protein+expression

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Virus-Like Particles That Can Deliver Proteins and RNA

Abstract: The National Cancer Institute's Protein Expression Laboratory seeks parties interested in licensing the novel delivery of RNA to mammalian cells using virus-like particles. Current methods of delivering proteins or RNA to mammalian cells are limited by a lack of target specificity and toxicity, among other shortcomings. NCI researchers have...

Published: 4/8/2024 | Inventor(s): Stanislaw Kaczmarczyk, Deb Chatterjee

Keywords(s): antibody synthesis, Protein Expression, RNA delivery, virus-like particles

Category(s): Application > Therapeutics, TherapeuticArea > Oncology, Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease

Tni-FNL: An Improved Trichoplusia Ni Cell Line for Protein Expression

Abstract: Researchers at the National Cancer Institute (NCI) have developed an improved insect cell line, Tni-FNL, derived from the cabbage looper, Trichoplusia ni. The Tni-FNL cell line is capable of high level expression of heterologous proteins using baculovirus-based expression systems. When compared to commercially available cell lines used for...

Published: 5/22/2024 | Inventor(s): Dominic Esposito, Ralph (Butch) Hopkins, Veronica Roberts

Keywords(s): Baculovirus, Cell line, Esposito, Insect Cell, Protein Expression, Tni-FNL

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology