Search Results - dhanalakshmi+(donna)+chinnasamy

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Highly Efficient Gene Transfer into Primary and Expanded Human Natural Killer Cells by Lentiviral Transduction for Cancer Therapy

This technology includes an efficient lentiviral vector-based method for gene transfer into NK cells and demonstrates a stable and long-term robust expression of transgenes for the treatment of cancer. High gene transfer rates into primary cells being transduced and the ability to produce high titers of virus particles for large-scale transduction of...

Published: 8/12/2024 | Updated: 3/26/2024 | Inventor(s): Richard Childs, Dhanalakshmi (Donna) Chinnasamy

Keywords(s):

Category(s): Application > Therapeutics, Collaboration Sought > Licensing, ResearchProducts > Human Cell Lines, TherapeuticArea > Oncology

T Cell-Based Adoptive Transfer Immunotherapy for Polyomavirus-Associated Pathologies

Available for licensing are methods to generate T cells responsive to multiple polyomaviruses. The resulting T cell populations could be useful in treating immunosuppressed individuals with polyomavirus infections or polyomavirus-associated pathologies such as Merkel cell carcinoma (MCC), polyomavirus-associated nephropathy (PVAN), hemorrhagic cystitis,...

Published: 10/28/2024 | Updated: 12/6/2022 | Inventor(s): Dhanalakshmi (Donna) Chinnasamy, Pawel Muranski, Christopher Buck, John Barrett

Keywords(s): adoptive transfer, BKV, CB2AXX, CB6XXX, Immunotherapy, Merkel, MKV, Patent Category - Biotechnology, Polyoma, polyomavirus, viral, virus, VLXXXX, WJXXXX, XAXXXX, XEXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology, ResearchProducts > Antibodies, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Oncology