Search Results - immunohistochemistry

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Automated Cancer Diagnostic Tool of Detecting, Quantifying and Mapping Mitotically-Active Proliferative Cells in Tumor Tissue Histopathology Whole-Slide Images

Abstract: Cancer diagnosis is based on the assessment of patient biopsies to determine the tumor type, grade, and stage of malignancy. The proliferative potential of tumors correlates to their growth and metastasis. Visually identifying and quantifying mitotic figures (MF) in cancer biopsy tissue can be used as a surrogate for proliferative activity...

Published: 5/23/2024 | Inventor(s): Robert Simpson, Stephen Hewitt, Shelley Hoover, Munish Puri

Keywords(s): Cancer Biopsy, diagnostic, Hewitt, HS, IHC, Immunohistochemistry, MF, Mitotic Figure, Mitotic Hotspots, Simpson, Tissue Histopathology

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Software / Apps

Biomarker for Predicting Taxane Chemotherapy Outcome

Abstract: Over the past decades, taxanes such as paclitaxel and docetaxel have emerged as effective chemotherapy agents for breast cancer and other malignancies. Taxanes are effective in many patients, however, not all patients benefit from this type of chemotherapy. A significant need remains for a means of predicting clinical outcome from taxane-based...

Published: 4/8/2024 | Inventor(s): Sherry Yang, Sandra Swain

Keywords(s): APOPTOSIS, Biomarkers, Docetaxel, Immunohistochemistry, PACLITAXEL, pAkt, taxane

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, TherapeuticArea > Oncology