Search Results - jennifer+bradbury

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Cytochrome P450 CYP2J Polyclonal Antibodies and Recombinant Proteins for Immunoblotting and Metabolism Studies

This technology includes identified members of the mouse cytochromes P450 CYP2J subfamily and antibodies to them for P450 expression studies and metabolism research. Recombinant proteins of the CYP2J subfamily members have also been expressed. The CYP2J subfamily members have a wide tissue distribution and may be useful as model systems for studies...

Published: 8/12/2024 | Inventor(s): Joan Graves, Darryl Zeldin, Joyce Goldstein, Jennifer Bradbury, Joyce Blaisdell

Keywords(s):

Category(s): Application > Research Materials, ResearchProducts > Antibodies, ResearchProducts > Plasmids/Vectors, TherapeuticArea > Metabolic Disease

Development of Reagents to Examine the Expression and Function of CYP2J Subfamily P450s

Cytochrome P450s catalyze the metabolism of a wide range of exogenous compounds, including drugs, industrial chemicals, environmental pollutants, and carcinogens. The 2C family of cytochrome P450 metabolizes an extensive number of drugs which include tolbutamide, S-Warfarin, mephenytoin, diazepam and taxol. The inventors cloned the cDNAs for several...

Published: 7/25/2024 | Inventor(s): Darryl Zeldin, Jennifer Bradbury

Keywords(s): CYP2J, Development, Examine, Expression, FUNCTION, Listed LPM Contreras as of 4/15/2015, P450s, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, R1XXXX, REAGENTS, RXXXXX, SUBFAMILY

Category(s): Collaboration Sought > Collaboration, Application > Research Materials