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A Novel Reagent for Labeling PET Tracers at Trifluoromethyl Groups

The molecular imaging technique of positron emission tomography (PET) is an increasingly important tool in biomedical research and in drug discovery and development. Many small molecule drugs and potential PET radiotracers carry trifluoromethyl (CF3) groups. Because CF3 groups are generally considered to be metabolically stable, there is a strong interest...

Published: 10/28/2024 | Inventor(s): Mohammad Haskali, Victor Pike

Keywords(s): :, [11C]Fluoroalkanes, Added, AGENT, LABELING, Method, No-Carrier, PET, Producing, Radiotracers, VAXXXX, VCXXXX, VDXXXX, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, YAXXXX, YBXXXX, YFXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Geriatrics, Application > Software / Apps, TherapeuticArea > Psychiatry/Mental Health, TherapeuticArea > Neurology, Application > Medical Devices, TherapeuticArea > Immunology

Evans Blue Dye Derivatives for Serum Albumin Labeling

The invention is an imaging agent and method of use for imaging blood pools and the lymphatic system. The imaging agent binds with high affinity to serum albumin, the most abundant serum protein, and can be tagged with several isotopes making it suitable for magnetic resonance imaging or positron emission tomographic imaging. To date, only very few...

Published: 10/28/2024 | Inventor(s): Lixin Lang, Gang NIU, Xiaoyuan (Shawn) Chen

Keywords(s): Albumin, BLUE, CA2BXX, Evans Blue, fluorene-18, IA4AXX, LABELED, LABELING, Listed LPM Fenn as of 4/15/2015, Magnetic Resonance, PET, Pet imaging, positron emission, Positron-Emitting, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PXXXXX

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Oncology, Application > Consumer Products, Application > Diagnostics, Application > Research Materials