Search Results - radiotracers

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A Novel Reagent for Labeling PET Tracers at Trifluoromethyl Groups

The molecular imaging technique of positron emission tomography (PET) is an increasingly important tool in biomedical research and in drug discovery and development. Many small molecule drugs and potential PET radiotracers carry trifluoromethyl (CF3) groups. Because CF3 groups are generally considered to be metabolically stable, there is a strong interest...

Published: 7/25/2024 | Inventor(s): Mohammad Haskali, Victor Pike

Keywords(s): :, [11C]Fluoroalkanes, Added, AGENT, LABELING, Method, No-Carrier, PET, Producing, Radiotracers, VAXXXX, VCXXXX, VDXXXX, VEXXXX, VNXXXX, WBXXXX, WIXXXX, XDXXXX, XFXXXX, YAXXXX, YBXXXX, YFXXXX

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, Application > Non-Medical Devices, TherapeuticArea > Geriatrics, Application > Software / Apps, TherapeuticArea > Psychiatry/Mental Health, TherapeuticArea > Neurology, Application > Medical Devices, TherapeuticArea > Immunology

Radiotracers for Imaging P-glycoprotein Transporter Function

This invention offers technology to help treat certain brain diseases, such as Alzheimer's disease and Parkinson's, and may lead to more effective and personalized treatments. P-glycoprotein transporter (P-gp) acts as a pump at the blood-brain barrier to exclude a wide range of xenobiotics (e.g., toxins, drugs, etc.) from the brain and is also expressed...

Published: 7/25/2024 | Inventor(s): Sami Zoghbi, Neva Lazarous, Robert Innis, Victor Pike

Keywords(s): AA3XXX, AAXXXX, ABXXXX, Alzheimer disease 1, Alzheimer disease 3, Alzheimer disease 4, Alzheimer disease type 1, Alzheimer disease type 4, Alzheimer disease, familial, type 3, AXXXXX, BBXXXX, BCXXXX, FUNCTION, IMAGING, Parkinson disease 2, Parkinson disease 3, Parkinson disease 9, Parkinson disease, juvenile, autosomal recessive, Patent Category - Chemistry, P-GP, Radiotracers, Vivo

Category(s): Collaboration Sought > Collaboration