Search Results - serguei+kozlov

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Murine metastatic pancreatic adenocarcinoma cell lines

Abstract: Researchers at the National Cancer Institute (NCI) have developed orthotopic allograft models for pancreatic cancer that utilize low passage primary pancreatic adenocarcinoma cells or tumor fragments implanted into the cancer-free pancreata of recipient syngeneic immunocompetent mice. Tumor development in these models is more synchronized,...

Published: 5/29/2025 | Updated: 8/2/2023 | Inventor(s): Serguei Kozlov, Ludmila Szabova, Melanie Gordon, Myhaymin Kamal, Jerome Schlomer, Theresa Guerin, Theresa O'Sullivan, Terry Van Dyke

Keywords(s): ADENOCARCINOMA, CANCER, GEM-Derived Allograft, Inflammation, Kozlov, Mouse Models, Pancreatic

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials

Humanized Mouse Model to Study Mesothelin (MSLN) -targeted Cancer Therapeutics: Bl6/TPO Mice

Summary: The NCI Laboratory of Molecular Biology is seeking parties interested in licensing a genetically engineered mouse model expressing hMSLN in the thyroid gland for commercialization in the field of cancer therapeutics and research targeting mesothelin-expressing tumors. Description of Technology: Mesothelin (MSLN) is an antigen highly expressed...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Christine Alewine, Serguei Kozlov, Xianyu Zhang, Theresa Guerin, Theresa O'Sullivan, Norman Collins, Jerome Schlomer

Keywords(s): Alewine, Bl6/TPO, Cancer Animal Model, hMSLN, Humanized Mice, MESOTHELIN, MSLN, Murine Model, THYROID

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology