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Stat1LoxP (Stat1 tm1Mam ) Mouse Model for Oncology and Immunology Studies

Selective inactivation of Stat1 in mammary cells indicates that its effect as a tumor suppressor in breast is direct. STAT1 is considered a tumor suppressor, but it is not known if this effect occurs directly in mammary cells or secondarily by disrupting interferon signaling through the JAK/STAT1 pathway to induce immune responses. ERBB2/neu-induced...

Published: 4/8/2024 | Inventor(s): Lothar Hennighausen

Keywords(s): CCXXXX, CXXXXX, Mouse, STAT1, Stat1LoxP, Tm1Mam

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology