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Topical Sodium Nitrate Ointment for Sickle Cell Disease

Abstract: Chronic leg ulcers are a debilitating vasculopathic complication for some patients with sickle cell disease (SCD). Prevalence of leg ulcers varies based on age and geographic location; about 5-10% of all SCD patients may suffer leg ulcers. These leg ulcers are painful, result in infections, hospitalization, disability, and negatively impact...

Published: 4/8/2024 | Inventor(s): Haksong Jin, George Grimes, Deborah Sperling, Gopal Potti, Caterina Minniti-Crouch, Gregory Kato

Keywords(s): Blood Disorder, CREAM, Haksong, nitric oxide, Ointment, SCD, sickle cell disease, Sodium Nitrate, TOPICAL, Topical Therapeutic, Vascular Ulcers, Wound healing

Category(s): TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Cardiology, Collaboration Sought > Licensing

Pre-Biotic Formulation of Topical Chemicals for Use on Human Skin

Atopic dermatitis (AD) is a common, recurrent, chronic inflammatory skin disease that is a cause of considerable economic and social burden. It is one of the most prevalent skin disorders, affecting ~25% of children in developed and developing countries and is expected to continue to escalate. This increased rate of incidence has changed the focus of...

Published: 7/25/2024 | Inventor(s): Carlo Castillo, Ian Myles

Keywords(s): CHEMICALS, FORMULATION, Human, Pre-biotic, SKIN, TOPICAL

Category(s): Collaboration Sought > Collaboration