Search Results - triple+negative+breast+cancer

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Abstract: Scientists at the NCI developed a research tool, a murine cell line model (JygMC(A)) with a reporter construct, of spontaneous metastatic mammary carcinoma that resembles the human breast cancer metastatic process in a triple negative mammary tumor. The assay is useful for screening compounds that specifically inhibit pathways involved in...

Published: 8/13/2024 | Inventor(s): Nadia Castro, David Salomon, Frank Cuttitta

Keywords(s): ANGIOGENESIS, Cell line, Metastasis, Triple Negative Breast Cancer, tumorigenesis

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials

Use of Acetalax for Treatment of Triple Negative Breast Cancer

Abstract: Triple negative (progesterone receptor (PR)-, estrogen receptor (ER)-, human epidermal growth receptor 2 (HER2)-) breast cancer (TNBC) is an aggressive subtype that affects 15-20% of the 1.7 million cases of breast cancer occurring annually. Currently, standard treatments of TNBC include cytotoxic chemotherapies, surgery, and radiation. However,...

Published: 4/8/2024 | Inventor(s): William Reinhold, Matthew Garnett, Vinodh Rajapakse, Yves Pommier, Augustin Luna

Keywords(s): Acetalax, Oxyphenisatin Acetate, Pommier, TNBC, Triple Negative Breast Cancer, Uterine Cancer

Category(s): Application > Therapeutics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology