Search Results - aggregation

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Removal of Selected Proteins Using Light Energy: Photoimmunotherapy

Abstract: Researchers at the NCI Laboratory of Molecular Theranostics and the Molecular Imaging Program have developed a new method to modify, isolate and remove a single chemically-labeled molecule or a cluster of proteins associated with the chemically-labeled protein. The chemical label can be an antigen-antibody complex. This discovery is based...

Published: 4/8/2024 | Inventor(s): Hisataka Kobayashi, Martin Schnermann, Peter Choyke

Keywords(s): AGGREGATION, Fluorophore, IR700, photoactivation, Photoimmunotherapy

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Collaboration Sought > Collaboration, TherapeuticArea > Oncology

Collagen-Induced Platelet Aggregation Inhibitor from Mosquito Salivary Glands

Exposed collagen in injured blood vessels provides a substrate for platelets to adhere and aggregate initiating the first step in thrombosis, the formation of blood clots inside a blood vessel. Despite the essential role of platelets in vascular injury, excessive platelet aggregation may also result in thrombotic diseases such as stroke and heart attack. Available...

Published: 7/25/2024 | Inventor(s): Eric Calvo

Keywords(s): AGGREGATION, Collagen-platelet, GLANDS, IB1EXX, IB1XXX, IB3XXX, IBXXXX, inhibitor, IXXXXX, Malaria, Mosquito, Salivary

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Immunology, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Cardiology, Application > Therapeutics