Search Results - fluorophore

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A New Class of Stable Heptamethine Cyanine Fluorophores and Biomedical Applications Thereof

Abstract: Heptamethine cyanines are among the most widely used near-IR fluorophores. The near-IR range (between about 650 nm and 900 nm) is very useful for imaging applications due to the absence of background autofluorescence. Despite extensive use, many of these fluorophores suffer from chemical instability. Specifically, most of the current and commonly...

Published: 4/8/2024 | Inventor(s): Martin Schnermann, Roger Nani, James Shaum

Keywords(s): Antibody labeling, DYE, Fluorescence-activated cell sorting (FACS), Fluorophore, Heptamethine Cyanines, IMAGING, Imaging Microscopy, Imaging reagent, MICROSCOPY, near-IR fluorophores, Optical-Guided Surgery

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Research Materials, Collaboration Sought > Collaboration

Removal of Selected Proteins Using Light Energy: Photoimmunotherapy

Abstract: Researchers at the NCI Laboratory of Molecular Theranostics and the Molecular Imaging Program have developed a new method to modify, isolate and remove a single chemically-labeled molecule or a cluster of proteins associated with the chemically-labeled protein. The chemical label can be an antigen-antibody complex. This discovery is based...

Published: 4/8/2024 | Inventor(s): Hisataka Kobayashi, Martin Schnermann, Peter Choyke

Keywords(s): AGGREGATION, Fluorophore, IR700, photoactivation, Photoimmunotherapy

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Collaboration Sought > Collaboration, TherapeuticArea > Oncology