Search Results - conjugates

2 Results

Sort By:

Diisocyanate Specific Monoclonal Antibodies for Occupational and Environmental Monitoring of Polyurethane Production Exposure-related Asthma and Allergy and Clinical Diagnosis

CDC researchers have developed monoclonal antibodies useful as diagnostics for diisocyanate (dNCO) exposure and for toxicity characterization of specific dNCOs. Currently, dNCOs are used in the production of all polyurethane products and are the most commonly reported cause of occupational-induced asthma and also linked to allergic contact dermatitis....

Published: 7/25/2024 | Inventor(s): Donald Beezhold, Tinashe Ruwona, Detlef Schmechel, Victor Johnson, Paul Siegel

Keywords(s): AAXXXX, AC5XXX, ACXXXX, AE2AXX, AE2CXX, AE2XXX, AE3XXX, AEXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Compositions, CONJUGATES, IA2XXX, IA3XXX, IA5XXX, IAXXXX, IDXXXX, Isocyanate, IXXXXX, Methods, NIOSH-HELD, Relating, VPXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, WJXXXX, WMXXXX, XAXXXX, XCXXXX, XIXXXX, YAXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, ResearchProducts > Antibodies, Application > Diagnostics, Application > Research Materials, Application > Occupational Safety and Health, Application > Therapeutics, TherapeuticArea > Infectious Disease, TherapeuticArea > Immunology, TherapeuticArea > Oncology, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, TherapeuticArea > Dental, Application > Consumer Products, TherapeuticArea > Pulmonology, TherapeuticArea > Cardiology, TherapeuticArea > Dermatology

N-Methanocarba Adenosine Derivatives and Their Dendrimer Conjugates as A3 Receptor Agonists

This technology relates to specific (N)-methanocarba adenine nucleosides that have been developed and dendrimers that connect these compounds to create molecules with multiple targets. Dendrimers are essentially repeated molecular branches presenting the core receptor-binding molecules. The compounds synthesized function as agonists and antagonists...

Published: 7/25/2024 | Inventor(s): Dilip Tosh, Kenneth Jacobson

Keywords(s): A3, ADENOSINE, AGONISTS, CONJUGATES, DENDRIMER, Derivatives, IAXXXX, IBXXXX, IXXXXX, N-Methanocarba, OBXXXX, OXXXXX, Patent Category - Chemistry, RECEPTOR, Their

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Ophthalmology, Application > Diagnostics, Application > Research Materials, Application > Therapeutics