Search Results - kuan-teh+jeang+(estate)

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Mouse Monoclonal Antibodies to MAD1, a Human Spindle Assembly Checkpoint Protein for Maintaining Chromosomal Segregation

Scientists at the National Institutes of Health have developed mouse monoclonal antibodies against the human spindle assembly checkpoint protein, MAD1. The spindle assembly checkpoint in mitotic cell division regulates the fidelity of chromosome segregation during cell division. MAD1 is an important component of this checkpoint control, which if compromised,...

Published: 7/25/2024 | Inventor(s): Kuan-teh Jeang (Estate)

Keywords(s): (4)r syndrome, Against, ANEUPLOIDY, antibodies, ASSEMBLY, C syndrome, CAXXXX, CC2XXX, CCXXXX, CHECKPOINT, Chromosome 4 ring syndrome, Chromosome 6 ring syndrome, Chromosome 7 ring syndrome, CXXXXX, G syndrome, Human, Hypertelorism with esophageal abnormality and hypospadias, MAD1, monoclonal, Mouse, N syndrome, Protein, R(6) syndrome, R(7) syndrome, spindle, Syndrome X, W syndrome, W syndrome; Syndrome W

Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Diagnostics, Application > Research Materials

Mouse Monoclonal Antibodies Against Human IKKgamma/NEMO Protein

NF-kB has been found to be important in immune responses, cell proliferation, apoptosis, and in organ development. Several years ago it was discovered that an IKKgamma/NEMO protein was essential as an adaptor molecule to mediate TNF-alpha, IL-1, and oncoprotein induced activation of NF-kB. Mutation in IKKgamma/NEMO also results in two human genetic...

Published: 7/25/2024 | Inventor(s): Kuan-teh Jeang (Estate)

Keywords(s): Ectodermal dysplasia, IAXXXX, IDXXXX, Incontinentia pigmenti, IXXXXX, Neurofibromatosis type 2, Neurofibromatosis type 3, NF 2, NF 3, RXXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, Application > Diagnostics, Application > Therapeutics