Search Results - masaki+terabe

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Multi-epitope Vaccines against TARP (ME-TARP) for Treating Prostate and Breast Cancer

Abstract: The development of more targeted means of treating cancer is vital. One option for a targeted treatment is the creation of a vaccine that induces an immune response only against cancer cells. In this sense, vaccination involves the introduction of a peptide into a patient that causes the formation of antibodies or T cells that recognize the...

Published: 4/8/2024 | Inventor(s): Lauren Wood, Jay Berzofsky, Brenda Roberson, Masaki Terabe

Keywords(s): BREAST CANCER, CANCER VACCINE, Immunotherapy, PROSTATE CANCER

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Vaccines

3-o-sulfo-galactosylceramide Analogs as Activators of Type II Natural Killer T (NKT) Cells to Reduce Cancer Metastasis to the Lung

Abstract: Lung metastases are a sign of widespread cancer with poor survival rate. Lung malignancies can originate from almost any cancer type spread via the blood stream. Most common lung metastases are from melanoma, breast cancer, bladder cancer, colon cancer, prostate cancer, neuroblastoma, and sarcoma. Living more than 5 years with lung metastases...

Published: 8/5/2024 | Inventor(s): Lise Pasquet, Jay Berzofsky, Amy Howell, Masaki Terabe, Kaddy Camara

Keywords(s): 3-o-sulfo-galactosylceramide Analogs, Berzofsky, C24:2, Immunotherapy, lung cancer, Metastasis, Natural Killer cells, NKT cells, Sulfatide Analogs, T Cells

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Immunology

Cancer Vaccines against POTE for Treating Solid Tumors

Abstract: POTE is a novel tumor antigen expressed in a variety of cancers including breast, prostate, colon, lung, ovary, and pancreas cancers. POTE has limited expression in normal tissues and therefore a specific target for cancer treatments, including immunotherapy. The researchers seek statements of capability or interest from parties interested...

Published: 8/5/2024 | Inventor(s): Jay Berzofsky, Yi-Hisang Huang, Masaki Terabe, Ira Pastan

Keywords(s): CANCER, immunogenic peptides, Immunotherapy, POTE, Vaccine

Category(s): Application > Vaccines, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology

Cancer Therapeutic based on Stimulation of Natural Killer T-cell Anti-tumor Activity

Abstract: Natural killer T cells (NKT) are a unique lymphocyte population that has T-cell and NK cell functional properties in order to rapidly elicit an immune response. alpha-galactosylceramide (alpha-GalCer) is a potent NKT stimulator and induces of IFN-gamma release to promote immunity against tumors and infectious agents. Humans have natural...

Published: 4/8/2024 | Inventor(s): Masaki Terabe, Jessica O'Konek, Petr Illarionov, Jay Berzofsky, Gurdyal Besra

Keywords(s): ANTIBODY, Immunity, NKT activity

Category(s): Application > Therapeutics, TherapeuticArea > Immunology, TherapeuticArea > Oncology, Collaboration Sought > Licensing