Search Results - mimetic

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Boron Amino Acid Mimetics for PET Imaging of Cancer

Available for licensing and commercial development as imaging agents for positron emission tomography of cancer are boramino acid compounds. The inventors showed that mimetics created by substituting the carboxylate group (-COO-) of an amino acid with trifluoroborate (-BF3-) are metabolically stable and allow for the use of fluorene-18 (18F) as the...

Published: 7/25/2024 | Inventor(s): Zhibo Liu, Xiaoyuan (Shawn) Chen

Keywords(s): AA3CXX, Boramino, CA1CXX, CA2BXX, CA2CXX, Cancer diagnosis, Cancer diagnostic, fluorene-18, Mimetic, MIMETICS, positron emission, VCXXXX, WBXXXX, WIXXXX, XFXXXX, YAXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials, Application > Medical Devices, Application > Diagnostics, Application > Non-Medical Devices, Application > Software / Apps, TherapeuticArea > Oncology

Therapeutic Peptide Treatment for Dyslipidemic and Vascular Disorders

This invention is directed to use of certain peptide analogs comprising multiple amphipathic helical domains that are able to promote cellular lipid efflux and stimulate lipoprotein lipase activity. As a result, administration of invention peptides lead to reduced incidences of hypertriglyceridemia without inducing toxicity. Existing peptides that stimulate...

Published: 7/25/2024 | Inventor(s): Marcelo Amar, Alan Remaley

Keywords(s): 3-@hydroxyacyl-coa dehydrogenase deficiency, ApoA-I, HAD deficiency, HIS deficiency, Histidinemia, Hypertriglyceridemia, IB1XXX, IBXXXX, IXXXXX, Mimetic, Patent Category - Biotechnology, Peptides, VDXXXX, VHXXXX, WBXXXX, WJXXXX, YAXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Endocrinology, TherapeuticArea > Cardiology, Application > Diagnostics, Application > Research Materials