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SIRT1 KO Human Cell Lines Generated by CRISPR/Cas9-mediated DNA Editing
SIRT1, a NAD+-dependent protein deacetylase, is the most conserved member of the sirtuins family. Through deacetylation of a number of protein substrates that are important transcription factors or co-factors, SIRT1 regulates many vital biological processes such as metabolism, cellular stress response, stem cell pluripotency, and development. The present...
Published: 10/28/2024
|
Inventor(s):
Yi Fang
,
Xiaoling Li
Keywords(s):
Cell
,
CRISPER/Cas9-mediated
,
DNA
,
Editing
,
GENERATED
,
Human
,
KO
,
Lines
,
SIRT1
,
VCXXXX
,
VFXXXX
,
VPXXXX
,
WIXXXX
,
XEXXXX
,
YAXXXX
Category(s):
Collaboration Sought > Licensing
,
TherapeuticArea > Ophthalmology
,
TherapeuticArea > Cardiology
,
TherapeuticArea > Endocrinology
,
TherapeuticArea > Dental
,
Application > Therapeutics
,
TherapeuticArea > Oncology
,
TherapeuticArea > Infectious Disease
,
Application > Research Materials
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