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Mouse Monoclonal Antibodies to MAD1, a Human Spindle Assembly Checkpoint Protein for Maintaining Chromosomal Segregation
Case ID:
TAB-1884
Web Published:
12/6/2022
Description:
Scientists at the National Institutes of Health have developed mouse monoclonal antibodies against the human spindle assembly checkpoint protein, MAD1. The spindle assembly checkpoint in mitotic cell division regulates the fidelity of chromosome segregation during cell division. MAD1 is an important component of this checkpoint control, which if compromised, can lead to the initiation of cancer cell growth. These monoclonal antibodies are the first available antibodies against MAD1 and can be used in laboratory research and diagnostics.
Patent Information:
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Patent No.
File Date
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Direct Link:
https://nih.technologypublisher.com/tech?title=Mouse_Monoclonal_Antibodies_to _MAD1%2c_a_Human_Spindle_Assembly_Checkpoint_Protein_for_Maintaining_Chromos omal_Segregation
Category(s):
Collaboration
Oncology
Diagnostics
Research Materials
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For Information, Contact:
Carol Salata
Technology Development Manager
NIH Technology Transfer
240-627-3727
csalata@mail.nih.gov
Inventors:
Kuan-teh Jeang (Estate)
Keywords:
(4)r syndrome
Against
ANEUPLOIDY
antibodies
ASSEMBLY
C syndrome
CAXXXX
CC2XXX
CCXXXX
CHECKPOINT
Chromosome 4 ring syndrome
Chromosome 6 ring syndrome
Chromosome 7 ring syndrome
CXXXXX
G syndrome
Human
Hypertelorism with esophageal abnormality and hypospadias
MAD1
monoclonal
Mouse
N syndrome
Protein
R(6) syndrome
R(7) syndrome
spindle
Syndrome X
W syndrome
W syndrome; Syndrome W
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