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Virus Microneutralization Assay Data Analysis for Vaccine Development, Enhancement and Efficacy Improvement
Case ID:
TAB-2742
Web Published:
12/6/2022
Description:
This CDC generated invention entails improved methods of analyzing microneutralization assays, especially for the purposes of determining specific antibody concentrations and optimizing vaccine formulation. More specifically, the invention is a set of SAS based programs using 4-parameter logistic curve fitting algorithms to interpolate between individual data points, allowing for enhanced accuracy and precision when establishing neutralization titers. This method allows every experiment to be analyzed the same way, provides greater accuracy by interpolating curve fits between dilutions, prevents transcription errors or manual calculation errors, develops and applies consistent quantitative control rules, and improves operational speed and efficiency.
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Direct Link:
https://nih.technologypublisher.com/tech?title=Virus_Microneutralization_Assa y_Data_Analysis_for_Vaccine_Development%2c_Enhancement_and_Efficacy_Improvement
Category(s):
Licensing
Antibodies
Immunology
Research Materials
Software / Apps
Research Equipment
Diagnostics
Infectious Disease
Occupational Safety and Health
Computational models/software
Therapeutics
Vaccines
Consumer Products
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For Information, Contact:
Inteum Admin
NIH Technology Transfer
Inventors:
Kathy Hancock
Jarad Schiffer
Keywords:
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analysis
assay
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CDC Docket Import
CDC Docket Import CDC Prosecuting
CONSTRAINTS
CURVE-FITTING
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DB4XXX
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MICRONEUTRALIZATION
OID-NCIRD-DBD
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WCXXXX
WFXXXX
WHXXXX
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