Search Results - 47+xyy+syndrome

7 Results

Sort By:

Enriched Natural Killer Cells for Adoptive Infusion Cancer Therapy

Immuno-therapy has taken a lead among the new cancer therapeutic approaches. It is one of the most promising new therapeutic approaches that exploit the innate immune mechanism of an individual to fight against a certain disease. Natural killer (NK) cells are a form of cytotoxic lymphocytes which constitute a major portion of the innate immune system....

Published: 7/25/2024 | Inventor(s): Richard Childs

Keywords(s): 47 XYY syndrome, BBXXXX, CB6XXX, CBXXXX, CXXXXX, Double Y

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, TherapeuticArea > Immunology, Application > Therapeutics

Recombinant MVA Viruses Expressing Clade A/G and Clade B Modified HIV Env, Gag and Pol Genes Useful for HIV Vaccine Development

The current technology relates to the construction, characterization and immunogenicity of modified vaccinia Ankara (MVA) recombinant viruses. The MVA double recombinant viruses express modified/truncated HIV-1 Env and mutated HIV Gag Pol under the control of vaccinia virus early/late promoters. This technology describes the MVA double recombinant...

Published: 7/25/2024 | Inventor(s): Linda Wyatt, Bernard Moss

Keywords(s): 47 XYY syndrome, DC5AXX, DCXXXX, Double Y, DXXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Vaccines

Wild-Type and DNA Polymerase beta Null Mouse Embryotic Fibroblast Cell Lines Harboring a lambda-LIZ Transgene

Of great utility in toxicology and DNA repair research are knockout mice with cell lines enabling one to evaluate generations of gene mutations as a direct function of base excision repair. Of particular importance are lambda-LIZ transgenes. Likewise, wild-type and beta-pol null cell lines are equally important. While there exist cell lines carrying...

Published: 7/25/2024 | Inventor(s): Robert Sobol

Keywords(s): 3-@hydroxyacyl-coa dehydrogenase deficiency, 47 XYY syndrome, AC5XXX, ACXXXX, AXXXXX, B, Cell, DNA, Double Y, Embryonic, Fibroblast, HAD deficiency, harboring, HIS deficiency, Histidinemia, KO, Lines, Mouse, NULL, polymerase, SV40T-Ag, TRANSFORMED, TRANSGENE, WILD-TYPE, Y-LIZ

Category(s): Collaboration Sought > Licensing

Anti-Vaccinia Monoclonal Antibody

The current technology describes a monoclonal antibody that reacts with a vaccinia virus protein abundantly expressed under an early viral promoter after infection of cells. The antibody is useful for quantitating vaccinia virus infected cells and for studying the function of the protein to which it binds, which is known to be a double stranded RNA...

Published: 7/25/2024 | Inventor(s): Jonathan (Jon) Yewdell

Keywords(s): 47 XYY syndrome, DDXXXX, Double Y, DXXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Infectious Disease, Application > Research Materials

A Mouse Model for Human Osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis and affects more than 20 million Americans, costing billions of dollars in health care annually. Osteoarthritis is caused by the breakdown of joint cartilage, leading to a loss of the cartilage "cushion" between the bones of the joints. Risk factors associated with OA include age, obesity, traumatic...

Published: 7/25/2024 | Inventor(s): Ake Oldberg, Tianshun Xu, Marian Young, Laurent Ameye

Keywords(s): 47 XYY syndrome, BAXXXX, Double Y, IBXXXX, IDXXXX, IXXXXX

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, ResearchProducts > Animal Models

Specific Inhibition of Gene Expression by Small Double Stranded RNAs

Double-stranded RNA (dsRNA) has been shown to trigger sequence-specific gene silencing in a wide variety of organisms, including plant, nematode and invertebrate species. Recent intense work in the field has shown that small dsRNAs mediate sequence specific RNA degradation in the process known as RNA interference (RNAi). This invention provides for...

Published: 4/8/2024 | Inventor(s):

Keywords(s): 47 XYY syndrome, Double Y, GBXXXX, GXXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics

Methods for the Identification of Textual and Physical Structured Query Fragments for the Analysis of Textual and Biopolymer Information

The invention comprises algorithms implemented in software for "structured combinatorial queries" that may be used for analyses of relatedness and information content in any textual information, and especially in biological sequences. The invention also includes experimental methods for isolating and comparing DNA fragments ("Structured Query Fragments"...

Published: 4/8/2024 | Inventor(s): Robert Boissy

Keywords(s): 47 XYY syndrome, ADXXXX, AXXXXX, Double Y

Category(s): Collaboration Sought > Licensing