Search Results - jeffrey+green

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GATA-3 Reporter Plasmids for Revealing Underlying Mechanisms in Breast Cancer

Abstract: GATA-3 is a transcription factor that is highly expressed in normal cells of the mammary luminal epithelium. GATA-3 plays a regulatory role in determining the fate of cells in the mammary gland. Disruption of GATA-3 expression leads to defects in the development of mammary cells, including an inability to differentiate properly into the correct...

Published: 7/25/2024 | Inventor(s): Hosein Kouros-Mehr, Jeffrey Green

Keywords(s): BREAST CANCER, diagnostic, GATA-3 expression, prognostic

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology

Transgenic Mouse Model of Human Basal Triple Negative Breast Cancer

Abstract: The NCI Laboratory of Cancer Biology and Genetics seeks parties interested in collaborative research to further develop this mouse model of triple-negative breast cancer (TNBC) to study cancer biology and for preclinical testing. As a Research Tool, patent protection is not being pursued for this technology; more information to access this...

Published: 5/23/2024 | Inventor(s): Jeffrey Green

Keywords(s): Mouse, Murine, PROSTATE, triple-negative breast cancer

Category(s): TherapeuticArea > Oncology, Application > Research Materials, Collaboration Sought > Licensing