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Hybridoma Cell Line D8H21, Monoclonal Antibody to the Specific Peptide-MHC Class II Complex
Hybridoma Cell Line D8H21, as described in Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13856-61 and developed in the laboratory of Dr. Ronald Germain.
Published: 7/25/2024
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Inventor(s):
Ronald Germain
Keywords(s):
Cell
,
D8H21
,
Hybridoma
,
Line
,
Listed LPM Hastings as of 4/15/2015
,
Mab
,
Post LPM Assignment Set 20150420
,
Pre LPM working set 20150418
,
RM
,
WIXXXX
Category(s):
Collaboration Sought > Licensing
,
Application > Research Materials
Amelioration of Inflammatory Arthritis Targeting the Pre-ligand Assembly Domain (PLAD) of Tumor Necrosis Factor Receptors
The invention relates to compositions of matter and methods for treating arthritis by modulating Tumor Necrosis Factor Alpha (TNF-alpha) signaling. TNF-alpha plays a key role in the pathogenesis of numerous diseases including rheumatoid and septic arthritis, and other autoimmune and inflammatory diseases. TNF-alpha mediates its effects through receptors...
Published: 7/25/2024
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Inventor(s):
Michael Lenardo
,
Francis Chan
,
Richard Siegel
Keywords(s):
ASSEMBLY
,
BCXXXX
,
CB3AXX
,
CBXXXX
,
CC1XXX
,
CCXXXX
,
CXXXXX
,
Domain
,
factor
,
FAMILY
,
FUNCTION.
,
Identification
,
Listed LPM Hastings as of 4/15/2015
,
Mediates
,
NECROSIS
,
Novel
,
Patent Category - Biotechnology
,
Post LPM Assignment Set 20150420
,
Pre LPM working set 20150418
,
PRE-LIGAND
,
RECEPTOR
,
SACGHS DNA Patent Initial Set
,
That
,
tumor
Category(s):
Collaboration Sought > Licensing
,
Application > Research Materials
,
Application > Therapeutics
,
TherapeuticArea > Oncology
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