Search Results - therapeuticarea+%3e+reproductive+health

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48-Position Custom Deep Well Plate For In Vitro Equilibrium Dialysis at a 1:1 Sample to Buffer Volume Ratio

CDC scientists have developed a new design for a multi-well dialysis microplate for equilibrium dialysis. The unique design accommodates a 1:1 buffer to sample ratio and provides additional room at the base of the well to enable optimal cartridge immersion and analyte diffusion. The microplate is readily adaptable into existing automated analytical...

Published: 4/10/2026 | Updated: 4/8/2026 | Inventor(s): Ashley Ribera, Hui Zhou, Hubert Vesper

Keywords(s):

Category(s): Application > Diagnostics, Application > Research Materials, Collaboration Sought, TherapeuticArea, TherapeuticArea > Endocrinology, TherapeuticArea > Geriatrics, TherapeuticArea > Hematology, TherapeuticArea > Obstetrics/Neo-Natal, TherapeuticArea > Reproductive Health, TherapeuticArea > Urology

First in class Small Molecule Agonists of the mammalian Relaxin family receptor 1 (RXFP1) and use in treatment of cancer, fibrotic, and vascular disorders (HHS Ref No. E-145-2024-0-US-02)

It is well documented in literature that activation of RXFP1 by relaxin induces: 1) up-regulation of the endothelin system which leads to vasodilation; 2) extracellular matrix remodeling through regulation of collagen deposition, cell invasiveness, proliferation, and overall tissue homeostasis; 3) a moderation of inflammation by reducing levels of inflammatory...

Published: 3/16/2026 | Updated: 5/29/2025 | Inventor(s): Juan Marugan, Mark Henderson, Kenneth Wilson, Wenwei Huang, Wenjuan Ye, Noel Southall, Jiankang Jiang, Khalida Shamim, Bing Li, Alexander Agoulnik, Abhijeet Kapoor, Joshua Hutcheson, Ana Cabrera, Irina Agoulnik

Keywords(s):

Category(s): Application > Therapeutics, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Cardiology, TherapeuticArea > Pulmonology, TherapeuticArea > Dermatology, TherapeuticArea > Reproductive Health, TherapeuticArea > Geriatrics

A Wearable Device for Monitoring Pregnancy Health

Summary: The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks research co-development partners and/or licensees for clinical validation and to further develop the technology. Description of Technology: Observing the placenta during pregnancy offers a look into the utero fetal environment. Monitoring...

Published: 4/23/2026 | Updated: 11/27/2023 | Inventor(s): Amir Gandjbakhche, Thien Nguyen, Zeyu Zhang, Soongho Park, George Downey, Alireza Khaligh, Kosar Khaksari

Keywords(s):

Category(s): Application, Application > Medical Devices, TherapeuticArea > Reproductive Health, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Levonorgestrel Butanoate Formulation and Methods Relating Thereto

Description of Technology: This invention is a potential subcutaneous or intramuscular progestin-only, injectable contraceptive for women. Forty-five percent (45%) of pregnancies in the United States are unintended. In this group, one-third of reproductive age women are obese – increasing the risk of diabetes, hypertension and venous thromboembolism...

Published: 4/23/2026 | Updated: 8/2/2023 | Inventor(s): Min Lee, Diana Blithe, Jia-Hwa Fang, Eduardo Ruiz, Ken Chen

Keywords(s): Blithe, CONTRACEPTIVE, INJECTABLE, LB, Lee, Levonorgestrel, Levonorgestrel Butanoate, LNG, National Institute of Child Health and Human Development, NICHD, Steroidal Progestin

Category(s): TherapeuticArea > Endocrinology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Reproductive Health

Mouse Embryo Culture Chamber and Imaging System and Methods of Use

Description of Technology: The culture of mouse embryos ex utero and continuous monitoring and imaging of embryos as they develop have applications in drug testing, genetic studies, and basic research on embryonic development. However, the embryo culture systems currently available for post-implantation embryos include rolling bottle culture systems,...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Vijay Kumar Kalaskar

Keywords(s): Culture Chamber, Embryo Development, Embryonic, FETAL, GENE THERAPY, IMAGING, In Vitro Drug Toxicology, Kalaskar, National Eye Institute, NEI, Organ System Therapy

Category(s): Application > Non-Medical Devices, TherapeuticArea > Reproductive Health, Application > Medical Devices, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

New Insect Sf9-ET Cell Line for Determining Baculovirus Titers

Abstract: The baculovirus-based protein expression system has gained increased prominence as a method for expressing recombinant proteins that are used in a wide range of biomedical applications. An important step in the use of this system is the ability to determine the virus infectious titer, i.e., the number of active baculovirus particles produced...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Ralph (Butch) Hopkins, Dominic Esposito

Keywords(s): Baculovirus, Baculovirus Titer, Esposito, IMMUNE, Inflammation, Insect Cell Line, Protein Expression Sf9-ET

Category(s): TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, Collaboration Sought > Licensing, TherapeuticArea > Reproductive Health, TherapeuticArea > Nephrology, Application > Research Materials, TherapeuticArea > Gastroenterology, TherapeuticArea > Endocrinology, TherapeuticArea > Dermatology, TherapeuticArea > Immunology, TherapeuticArea > Oncology, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

Monomeric and Oligomeric Compounds as Contraceptives and Endocrine Therapeutics

Summary: NICHD is seeking research co-development partners and/or licensees for development of this invention as a male contraceptive. Description of Technology: The options for male contraceptives are limited. Research is ongoing to develop a male contraceptive based on hormonal activity. Testosterone is one of the hormones necessary in producing...

Published: 4/24/2026 | Updated: 8/2/2023 | Inventor(s): Min Lee, Diana Blithe, Pranab Gupta, Bashir Kaskar, Ming-Teh Lin

Keywords(s): Blithe, CONTRACEPTIVE, Estrogenic Activity, Eunice Kennedy Shriver National Institute of Child Health an, Lee, Male Contraceptive, MONOMERIC, NCE, New Chemical Entity, NICHD, OLIGOMERIC

Category(s): Application > Therapeutics, TherapeuticArea > Reproductive Health, TherapeuticArea > Endocrinology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

A peptide hydrogel for use in vascular anastomosis

Abstract: In collaboration with surgery specialists from Johns Hopkins University, researchers at the National Cancer Institute (NCI) developed novel hydrogel compositions and methods of using them in the microsurgical suturing of blood vessels, which is particularly beneficial for surgeons in whole tissue transplant procedures. The lead candidate electropositive...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Joel Schneider, Gerald Brandacher, Daniel Smith, Gabriel Brat, Johanna Grahammer

Keywords(s): Anastomosis, Hydrogel, Microsurgery, Peptide, Schneider, Surgery

Category(s): TherapeuticArea > Oncology, TherapeuticArea > Endocrinology, Application > Non-Medical Devices, TherapeuticArea > Reproductive Health, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing, Application > Medical Devices, TherapeuticArea > Dermatology, TherapeuticArea > Immunology, TherapeuticArea > Gastroenterology, TherapeuticArea > Cardiology, TherapeuticArea > Nephrology, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

Nandrolone 17 Beta-Carbonates

Summary: Researchers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development are highly motivated in seeking licensing and/or collaboration partners for the development and use of androgenic compounds as contraceptives and/or hormonal therapeutics. Description of Technology: The available options for male contraceptives...

Published: 4/23/2026 | Updated: 8/2/2023 | Inventor(s): Richard Blye, Hyun Kim, Min Lee

Keywords(s): 19-nortestosterone, Androgenic Compounds, Blye, Male Contraceptive, Nandrolone, National Institute of Child Health and Human Development, NICHD

Category(s): TherapeuticArea > Endocrinology, Collaboration Sought > Licensing, Application > Therapeutics, Collaboration Sought > Collaboration, TherapeuticArea > Reproductive Health

Bac-2-the-Future: An Improved System for Production of Recombinant Baculovirus

Abstract: Baculoviruses have been used for decades to produce proteins in insect cell hosts. Current systems for generating recombinant baculovirus have several shortcomings which prevent their easy use in high-throughput applications. Researchers within the Frederick National Laboratory for Cancer Research have developed an improved system called...

Published: 4/22/2025 | Updated: 8/2/2023 | Inventor(s): Dominic Esposito, Carissa Grose

Keywords(s): B2F, Bac-2-the-Future, Baculovirus, Esposito, Insect Cells, Protein Production

Category(s): TherapeuticArea > Gastroenterology, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, TherapeuticArea > Reproductive Health, TherapeuticArea > Immunology, TherapeuticArea > Dermatology, Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Oncology, TherapeuticArea > Nephrology, TherapeuticArea > Ear, Nose, & Throat, TherapeuticArea > Ophthalmology

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