Search Results - chimpanzee

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Humanized Monoclonal Antibodies Efficient for Neutralization of Tick-Borne Encephalitis Virus (TBEV)

TBEV causes serious illnesses from meningitis to meningo-encephalitis, totaling 3,000 cases of hospitalization in Europe and between 5,000-10,000 cases in Russia reported every year. The Far Eastern hemorrhagic TBEV strains are associated with a mortality rate (between 1-2%), higher than other strains isolated in the Siberia or Western Europe. There...

Published: 7/25/2024 | Inventor(s): Alexander Pletnev, Ching-juh Lai, Robert Purcell

Keywords(s): antibodies, ANTIBODY, Binding/Neutralization, Chimpanzee, DA4BXX, DA4XXX, DAXXXX, DB4BXX, DB4XXX, DBXXXX, DDXXXX, DERIVED, DXXXXX, Efficient, ENCEPHALITIS, FAB, Fragments, HUMANIZED, monoclonal, TBEV, TICK-BORNE, virus

Category(s): Collaboration Sought > Collaboration, Application > Diagnostics, Application > Research Materials, Application > Therapeutics, TherapeuticArea > Infectious Disease

Monoclonal Antibodies That Bind or Neutralize Hepatitis B Virus

Hepatitis B virus (HBV) chronically infects over 300 million people worldwide. Many of them will die of chronic hepatitis or hepatocellular carcinoma. The present technology relates to the isolation and characterization of a novel neutralizing chimpanzee monoclonal antibody to HBV. The antibody was identified through a combinatorial antibody library...

Published: 7/25/2024 | Inventor(s): Robert Purcell, Suzanne Emerson

Keywords(s): ANTIBODY, B, Chimpanzee, DB4BXX, DB4XXX, DBXXXX, DDXXXX, DXXXXX, Hepatitis, Hepatitis A, Hepatitis D, Hepatitis E, monoclonal, Neutralizes, That, virus

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Infectious Disease, Application > Therapeutics