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This invention aims to bolster the human body's own mechanisms to fight infection by enhancing an innate immune response, opsonophagocytosis. The specific 24 amino acid sequence (P4) acts as a polymorphonuclear cell activator. P4 can be administered in vivo along with a disease's specific antibody to enhance systemic bacterial clearance, thus leading...

Published: 7/25/2024 | Inventor(s): GowriSankar Rajam, Sandra Steiner, George Carlone, Nikkol Atwell-Melnick Melnick, Jacquelyn Sampson, Joseph Martinez, Joseph Caba, Edwin Ades

Keywords(s): ANTIGEN, CDC Docket Import, CDC Docket Import CDC Prosecuting, DA3XXX, DAXXXX, DB3XXX, DB5XXX, DBXXXX, DC1XXX, DC4XXX, DCXXXX, DXXXXX, ENHANCING, Epitopes, FUNCTIONAL, Listed LPM Surabian as of 4/15/2015, Methods, OID-NCIRD-DBD, Opsonophagocytosis, PATHOGEN, PNEUMONIAE, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, PsaA, RESPONSE, Streptococcus, THEREOF, USES

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics, Application > Therapeutics, Application > Vaccines, TherapeuticArea > Infectious Disease

Contrast Agent Enhancement of Chemical Exchange Dependent Saturation Transfer (CEDST) MRI

Available for licensing is an MRI image improving system wherein at least one contrast agent is administered to a subject in amounts effective to perform chemical exchange dependent saturation transfer (CEDST) MRI analysis. Examples of contrast agents suitable for administration as exogenous contrast agents include at least one functional group bearing...

Published: 4/8/2024 | Inventor(s): Anthony Aletras, Kathleen Ward, Robert Balaban

Keywords(s): AA3AXX, AA3B1X, AA3BXX, AA3XXX, AAXXXX, AXXXXX, Contrast, CSalata, ENHANCING, IMAGES, IMAGING, Magnetic, Method, Patent Category - Mech/Elect/Soft, PRODUCED, Resonance

Category(s): Collaboration Sought > Licensing