Search Results - tbi

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Device for Simulating Explosive Blast and Imaging Biological Specimens

Abstract: Traumatic brain injury (TBI) is a major health problem. Between 3.2 and 5.3 million people live with long-term disabilities resulting from TBI, and thus, contribute to the need to develop therapies that treat TBI-induced cellular damage. Researchers at the National Institute of Child Health and Human Development (NICHD) have developed a device...

Published: 4/8/2024 | Inventor(s): Rea Ravin, Paul Blank, Alex Steinkamp, Joshua Zimmerberg, Sergey Bezrukov, Kim Lee Mcafee

Keywords(s): Central Nervous System, CNS, explosive blast, National Institute of Child Health and Human Development, NICHD, SIMULATOR, TBI, Traumatic Brain Injury, Zimmerberg

Category(s): Application > Non-Medical Devices, Collaboration Sought > Collaboration, Application > Medical Devices, TherapeuticArea > Neurology, Collaboration Sought > Licensing

Tamperless Tensor Elastography Imaging

Abstract: Measuring and mapping nervous tissue microstructure noninvasively is a long sought-after goal in neuroscience. Several neuropathologies – such as cancer and stroke – are associated with changes in tissue microstructure. Changes in material properties, such as stiffness, represent a sensitive measure of underlying changes in tissue architecture,...

Published: 4/8/2024 | Inventor(s): Peter Basser, Magdoom Mohamed Kulam Najmudeen

Keywords(s): Alzheimer’s Disease, Anisotropy, Basse, brain, CANCER, Elasticity Tensor, Elastography, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, Najmudeen, NICHD, TBI, TRAUMA, Traumatic Brain Injury

Category(s): TherapeuticArea > Neurology, Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing

MRI-Based Method for Characterizing Axonal Microstructure in Traumatic Brain Injury

Abstract: Neurites of the central nervous system can be conceptualized as cylindrical pores with finite lengths and radii. In response to physical trauma, axons may assume a “beaded” morphology which alters their ability to conduct electrical impulses, impairing brain function. These microstructural changes are thought to underlie some of the cognitive...

Published: 4/8/2024 | Inventor(s): Peter Basser, Dan Benjamini, Michal Komlosh

Keywords(s): Magnetic Resonance Imaging, MRI, MRI diagnostic, Neurites, Peripheral Nervous System, PNS, TBI, Traumatic Brain Injury

Category(s): Application > Diagnostics, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Neurology

Multidimensional MRI Signature for Specific Detection of Traumatic Brain Injury In Vivo

Abstract: Traumatic brain injury (TBI) represents a major medical, social and economic concern worldwide due to significant mortality – especially among younger populations – and long-term disabilities. Various pathological brain lesions (e.g., intracerebral bleedings, necrotic-ischemic lesions, tissue avulsion) are produced by impacting mechanical...

Published: 4/8/2024 | Inventor(s): Dan Benjamini, Peter Basser, Diego Iacono

Keywords(s): Amyloid Precursor Protein, Be, DAI, Diffuse Axonal Injury, Eunice Kennedy Shriver National Institute of Child Health an, Magnetic Resonance Imaging, MRI, MULTIDIMENSIONAL, NICHD, TAI, TBI, Traumatic Axonal Injury, Traumatic Brain Injury

Category(s): TherapeuticArea > Neurology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Diagnostics