Search Results - Application+%3e+Non-Medical+Devices

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Vitamin C renal leak as a clinical diagnostic tool in the detection, monitoring, and management of acute and chronic diseases

This technology includes a clinical diagnostic tool for measuring vitamin C elimination by human kidneys that can be used for detecting, monitoring, and managing acute and chronic diseases. Findings revealed significant associations between vitamin C renal leak status and clinical variables affecting renal function and blood glucose. The technology...

Published: 8/12/2024 | Inventor(s): Ifechukwude Ebenuwa, Pierre-Christian Violet, Mark Levine

Keywords(s):

Category(s): Application > Diagnostics, Application > Non-Medical Devices, Application > Research Materials, TherapeuticArea > Cardiology, TherapeuticArea > Endocrinology, TherapeuticArea > Metabolic Disease, TherapeuticArea > Neurology, Collaboration Sought > Licensing, Collaboration Sought > Collaboration

Apparatus for Cryogenic-Electron Microscopy Sample Preparation

Cryo-Electron Microscopy (cryo-EM) is used to obtain high-resolution structural images of macromolecular structures. Samples must be purified and loaded onto cryo-EM grids before imaging. The ideal cryo-EM grid consists of particles that are evenly and richly distributed in a broad distribution of orientations throughout the holes of the support film....

Published: 8/13/2024 | Inventor(s): Venkata Dandey, Mario Borgnia, Wyatt Peele, Tony Huang, Kaichun Yang

Keywords(s):

Category(s): Application > Non-Medical Devices, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, ResearchProducts > Research Equipment

Transperineal Ultrasound-Guided Prostate Biopsy

Abstract: Prostate cancer is the most common male cancer in the United States, and the third most common worldwide. Prostate biopsies are often performed to confirm a cancer diagnosis and examine suspect tissue. Prostate biopsies are most often performed under transrectal ultrasound imaging (TRUS) guidance. TRUS images in real-time, at relatively low...

Published: 4/8/2024 | Inventor(s): Bradford Wood, Sheng Xu, Reza Seifabadi

Keywords(s): guided biopsy, Prostate biopsy, Sensorless, transperineal 3-D ultrasound imaging, ultrasound-fusion image, WOOD

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices, TherapeuticArea > Oncology

Tissue Clamp for Repeated Opening and Closure of Incisions/Wounds

Abstract: Medical clamps currently available are not efficient nor are they sufficiently precise in closure and alignment of the edges of an incision or wound. Many available designs are difficult to use and handle, especially in situations where repeated opening and closure of an incision or wound is required. The functional short-comings of existing...

Published: 4/8/2024 | Inventor(s): Vladimir Khristov, Steven Charles, Juan Amaral, Arvydas Maminishkis, Kapil Bharti

Keywords(s): CLAMP, ocular surgery, sclera incision closure

Category(s): Collaboration Sought > Collaboration, Application > Non-Medical Devices, Application > Medical Devices, Collaboration Sought > Licensing, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat

Device for Simulating Explosive Blast and Imaging Biological Specimens

Abstract: Traumatic brain injury (TBI) is a major health problem. Between 3.2 and 5.3 million people live with long-term disabilities resulting from TBI, and thus, contribute to the need to develop therapies that treat TBI-induced cellular damage. Researchers at the National Institute of Child Health and Human Development (NICHD) have developed a device...

Published: 4/8/2024 | Inventor(s): Rea Ravin, Paul Blank, Alex Steinkamp, Joshua Zimmerberg, Sergey Bezrukov, Kim Lee Mcafee

Keywords(s): Central Nervous System, CNS, explosive blast, National Institute of Child Health and Human Development, NICHD, SIMULATOR, TBI, Traumatic Brain Injury, Zimmerberg

Category(s): Application > Non-Medical Devices, Collaboration Sought > Collaboration, Application > Medical Devices, TherapeuticArea > Neurology, Collaboration Sought > Licensing

Mouse Embryo Culture Chamber and Imaging System and Methods of Use

Abstract: The culture of mouse embryos ex utero and continuous monitoring and imaging of embryos as they develop have applications in drug testing, genetic studies, and basic research on embryonic development. However, the embryo culture systems currently available for post-implantation embryos include rolling bottle culture systems, which do not permit...

Published: 4/8/2024 | Inventor(s): Vijay Kalaskar

Keywords(s): Culture Chamber, Embryo Development, Embryonic, FETAL, GENE THERAPY, IMAGING, In Vitro Drug Toxicology, Kalaskar, National Eye Institute, NEI, Organ System Therapy

Category(s): Application > Non-Medical Devices, TherapeuticArea > Reproductive Health, Application > Medical Devices, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat

Automatic System and Method for Tissue Sectioning, Staining, and Scanning

Abstract: Computer and imaging technologies led to the development of digital pathology and the capture and storage of pathological specimens as digitally formatted images. The use of artificial intelligence (AI) in digital pathology, such as in three-dimensional (3D) reconstruction, requires analyses of high volumes of data. This results in increased...

Published: 4/8/2024 | Inventor(s): Zhengping (Ping) Zhuang, Young-Wan Moon

Keywords(s): AI, Artificial Intelligence, AUTOMATION, Digital Pathology, High-throughput, Histology, IMAGING, Zhuang

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Oncology, TherapeuticArea > Neurology, TherapeuticArea > Infectious Disease, Application > Medical Devices, Application > Non-Medical Devices

Synthetic Bacterial Nanoparticles as Drug and Vaccine Delivery Vehicles

Abstract: Bacterial spores can be modified to display molecules of interest, including drugs, immunogenic peptides, antibodies and other functional proteins of interest (such as enzymes). The resulting engineered bacterial spores can provide many useful functions such as the treatment of infections, use as an adjuvant for the delivery of vaccines,...

Published: 5/21/2024 | Inventor(s): Kumaran Ramamurthi, I-Lin Wu

Keywords(s): Bacterial Spore, Drug Delivery, Nanoparticle, Ramamurthi, SSHEL, Synthetic Spore Husk-encased Lipid Bilayer, VACCINE DELIVERY

Category(s): TherapeuticArea > Infectious Disease, Application > Non-Medical Devices, Application > Medical Devices, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology

Method for Targeted Therapeutic Delivery of Proteins into Cells

Abstract: Current methods to deliver proteins into cells (e.g., using retrovirus, DNA transfection, protein transduction, microinjection, complexing the protein with lipids, etc.) have many shortcomings, such as lack of target specificity toxicity, or unwanted random integration into the host chromosome. Protein transduction is an emerging technology...

Published: 4/8/2024 | Inventor(s): Deb Chatterjee, Stanislaw Kaczmarczyk

Keywords(s): virus-like particles, VLP

Category(s): TherapeuticArea > Oncology, Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices

Surgical Tool for Sub-retinal Tissue Implantation

Abstract: The accurate placement of transplanted tissue at a precise position in the retina is difficult but critical for a successful implementation of an ocular surgical intervention. Researchers at the National Eye Institute (NEI) developed a surgical tool (see image below) designed to place tissue patches, such as sheets of tissue, onto the retina...

Published: 4/8/2024 | Inventor(s): Arvydas Maminishkis

Keywords(s): EYE, Intra-Ocular, Maminishkis, National Eye Institute, NEI, sub-retinal, surgical tool, tissue placement retina

Category(s): Collaboration Sought > Licensing, Application > Non-Medical Devices, Application > Medical Devices, TherapeuticArea > Opthamology, TherapeuticArea > Eye / Ear / Nose / Throat

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