Search Results - joon-yong+chung

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Argon to Improve Bioanalyte Stability in Fixed Tissue Specimens

Abstract: The degradation of archival surgical and biospecimen limits the utility of many biomarkers that may have prognostic or predictive significance in guiding a patient’s therapy. Previous methods at preventing the degradation of RNA and proteins in formalin fixed, paraffin embedded (FFPE) tissue blocks & slides have no protective benefit. Researchers...

Published: 5/23/2024 | Inventor(s): Stephen Hewitt, Vasuhi Rasanayagam, Joon-Yong Chung, Sagar Joshi, Meenakshi Sundar

Keywords(s): Anatomic Pathology Tissue Handling Improvements, ARGON, DNA, FFPE, formaldehyde, Formalin Fixed Paraffin Embedded, Hewitt, Paraffin Embedded, RNA

Category(s): Application > Diagnostics, TherapeuticArea > Oncology, Collaboration Sought > Licensing

Novel Fixative for Improved Biomolecule Quality from Paraffin-Embedded Tissue

Abstract: Tissues samples collected during medical procedures, such as biopsies, are used to diagnose a wide variety of diseases. Before diagnosis, patient samples are typically processed by fixation and paraffin embedding. This fixation/embedding process is used to preserve tissue morphology and histology for subsequent evaluation. Unfortunately, most...

Published: 4/8/2024 | Inventor(s): Stephen Hewitt, Candice Perry, Joon-Yong Chung, Robert Star

Keywords(s): CULTURE, fixative, Histology, PARAFFIN, PATHOLOGY, Tissue

Category(s): Collaboration Sought > Licensing, Application > Medical Devices, TherapeuticArea > Oncology, Application > Non-Medical Devices

Ratio Based Biomarkers for the Prediction of Cancer Survival

Abstract: The AKT pathway plays a key role in the regulation of cellular survival, apoptosis, and protein translation and has been shown to have prognostic significance in a number of cancers. Recently, the inventors have identified several functions of the AKT pathway in certain cancers, such as extrahepatic cholangiocarcinoma (EHCC). The NCI seeks...

Published: 4/8/2024 | Inventor(s): Stephen Hewitt, Joon-Yong Chung, Udayan Guha

Keywords(s): AKT pathway, diagnostic, extrahepatic cholangiocarcinoma, prognostic

Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, Application > Diagnostics, TherapeuticArea > Oncology