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Reducing Bloodstream Neutrophils as a Treatment for Lung Infection and Inflammation

During lung infection, bloodstream neutrophils (PMNs) responding to infection travel to the airspace lumen. Although successful arrival of microbicidal PMNs to the airspace is essential for host defense against inhaled pathogens, excessive accumulation of PMNs in the lung contributes to the pathogenesis of several prevalent lung disorders, including...

Published: 7/25/2024 | Inventor(s): Carmen Williams, Wan-Chi Lin, Michael Fessler

Keywords(s): 2, BARRIER, DA1XXX, DA3XXX, DA4XXX, DAXXXX, DBXXXX, During, DXXXXX, Epithelial, Infection, Inflammation, INTEGRITY, LUNG, MEMBRANE, PROTECT, Protein, respiratory, Targeting, VJXXXX, VKXXXX, VLXXXX, VPXXXX, WBXXXX, WJXXXX, WKXXXX, XAXXXX, YAXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, ResearchProducts > Antibodies, Application > Diagnostics, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Endocrinology, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, TherapeuticArea > Dental, TherapeuticArea > Immunology, TherapeuticArea > Oncology

Java Applet for Modeling Human Metabolism and Energy Expenditure for Adaptive Dieting and Exercise Regimens

Known methods for predicting weight loss fail to account for slowing of metabolism as weight is lost and therefore overestimate the degree of weight loss. While this limitation of the 3500 Calorie per pound rule has been known for some time, it was not clear how to dynamically account for the metabolic slowing. The invention provides a Java applet for...

Published: 7/25/2024 | Inventor(s): Dhruva Chandramohan, Carson Chou, Kevin Hall

Keywords(s): AC2XXX, ACXXXX, AD1XXX, Adaptions, Adn, Adult, ADXXXX, AXXXXX, Body, CHANGES, Dieting, During, Energy, EXERCISE, Expenditure, Fat, Human, ID2XXX, IDXXXX, IXXXXX, Mathematical, Metabolism, Model, PREDICTS, Simulates, That, Weight

Category(s): Collaboration Sought > Licensing, Application > Diagnostics, Application > Research Materials, Application > Therapeutics

Device and Method for Protecting Against Coronary Artery Compression During Transcatheter Mitral Valve Annuloplasty

Catheter-based mitral valve regurgitation treatments that use a coronary sinus trajectory or coronary sinus implant can have unwanted effects because the coronary sinus and its branches have been found to cross the outer diameter of major coronary arteries in a majority of humans. As a result, pressure applied by any prosthetic device in the coronary...

Published: 7/25/2024 | Inventor(s): Ozgur Kocaturk, Robert Lederman, June-Hong Kim

Keywords(s): AA2XXX, AA4CXX, AA4XXX, AAXXXX, AB3FXX, AB3XXX, ABXXXX, Against, Annuloplasty, ARTERIAL, ARTERIES, AXXXXX, Compression, CORONARY, DEVICE, During, Mitral, PMVA, PROTECT, Transcatheter, Vale, Valve

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing

Image Guided Systems and Methods for Organ Viability Assessment

The number of patients for organ transplants continues to grow, without an increase in the number of organs available for transplant. This has increased interest in transplanting organs from non-traditional sources, such as donations after cardiac death. However, there are currently no methods to objectively measure the effects of resuscitation and...

Published: 7/25/2024 | Inventor(s): Allan Kirk, Eric Elster, Frederick Gage, Alexander Gorbach

Keywords(s): AA1XXX, AA3BXX, AA3XXX, AAXXXX, ASSESSMENT, AXXXXX, DEVICE, DONOR, During, Guided, Image, Method, ORGANS, ORS to NIBIB, Resuscitation, VIABILITY

Category(s): Collaboration Sought > Licensing