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Viral Like Particles Based Chikungunya Vaccines

Chikungunya virus (CHIKV) is mosquito-borne alphavirus endemic in Africa, India, and Southeast Asia. In 2013 CHIKV infection has also emerged in the Caribbean and a pandemic of CHIKV has re-emerged in the Philippines following Typhoon Haiyan. Currently, there is no vaccine available for the prevention of CHIKV infection and no specific therapy exists...

Published: 7/25/2024 | Inventor(s): Wataru Akahata, Srinivas Rao, Gary Nabel

Keywords(s): Against, ALPHA, ALPHAVIRUS, CAPSID, Chikungunya, CHIKV, DC5BXX, Development, DNA vaccine, E1, E1-E2, E2, Envelope, Generation, Method, MODIFICATION, Modifications, PARTICLES, Patent Category - Biotechnology, PLASMID, PREVENTIVE, production, Protein, proteins, Vaccine, VBXXXX, viral, virus, VIRUS-LIKE, VLPs, VLXXXX, XHXXXX

Category(s): Collaboration Sought > Licensing, Application > Therapeutics, TherapeuticArea > Infectious Disease, Application > Vaccines, Application > Diagnostics, ResearchProducts > Research Equipment

Air Quality Assurance: A Monitor for Continuous, Simultaneous Analysis of Atmospheric or Aerosolized Particulate Mixtures

This technology pertains to monitors for measuring the mass concentration of ambient particulate matter in an atmosphere containing both larger/coarser (e.g., respirable dust) and smaller/finer (sub-micrometer particles such as diesel particulate matter - DPM) particulate mixtures. The monitoring device can be configured for operation with a controller...

Published: 7/25/2024 | Inventor(s): Jon Volkwein, William Schiffbauer, Charles Litton

Keywords(s): AE1BXX, AE2BXX, AE2XXX, AE3XXX, AEXXXX, ANALYZING, apparatus, AXXXXX, CDC Docket Import, CDC Docket Import CDC Prosecuting, Ionization, Light-scattering, Methods, NIOSH-PRL, PARTICLES, SENSORS, WCXXXX, WEXXXX, WFXXXX, WGXXXX, WMXXXX, XDXXXX, XIXXXX, YEXXXX, YFXXXX

Category(s): Collaboration Sought > Licensing, Application > Medical Devices, Application > Occupational Safety and Health, Application > Non-Medical Devices, Application > Consumer Products

Virus Replicon Particles as Rift Valley Fever Vaccines

Rift Valley fever (RVF) virus primarily infects animals but also has the capacity to infect humans. The disease causes abortion and death among RVF-infected livestock, resulting in substantial economic loss to people living in many parts of Africa and Arabian Peninsula. Currently, there is no commercial vaccine for RVF. CDC scientists have developed...

Published: 7/25/2024 | Inventor(s): Cesar Albarino, Brian Bird, Stuart Nichol, Kimberly Dodd

Keywords(s): CDC Docket Import, CDC Docket Import CDC Prosecuting, DC5BXX, DC5XXX, DCXXXX, DXXXXX, FEVER, OID-NCEZID-DHCPP, PARTICLES, Replicon, RIFT, THEREOF, Valley, virus, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WFXXXX, WIXXXX, WJXXXX, WMXXXX, XAXXXX, XCXXXX, XEXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, ResearchProducts > Antibodies, Application > Research Materials, Application > Diagnostics, TherapeuticArea > Infectious Disease, TherapeuticArea > Cardiology, Application > Occupational Safety and Health, TherapeuticArea > Oncology, TherapeuticArea > Endocrinology, Application > Vaccines, Application > Consumer Products, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Dental

Non-radioactive, Miniature Bipolar Aerosol Particle Charger for Personal, Portable Instrumentation

This CDC developed invention is a novel device for a miniature, nonradioactive bipolar charger to electrically charge aerosol particles for use in personal and portable aerosol instrumentation. Such devices are an integral component of aerosol instruments employing electrical mobility-based techniques. Current, commercial state-of-the-art mobility...

Published: 7/25/2024 | Inventor(s): Chaolong Qi, Pramod Kulkarni

Keywords(s): AA2XXX, AA4BXX, AAXXXX, AE1XXX, AE2BXX, AE2XXX, AE3XXX, AEROSOL, AEXXXX, AFXXXX, AGXXXX, AXXXXX, BIPOLAR, CDC Docket Import, CDC Docket Import CDC Prosecuting, Charger, NIOSH-DART, NON-RADIOACTIVE, PARTICLES, VBXXXX, VJXXXX, VKXXXX, VLXXXX, VOXXXX, VPXXXX, WAXXXX, WBXXXX, WCXXXX, WFXXXX, WGXXXX, WIXXXX, WMXXXX, XDXXXX, XIXXXX, YEXXXX

Category(s): Collaboration Sought > Licensing, Application > Research Materials, TherapeuticArea > Ophthalmology, Application > Diagnostics, Application > Vaccines, Application > Occupational Safety and Health, TherapeuticArea > Dental, TherapeuticArea > Infectious Disease, TherapeuticArea > Endocrinology, Application > Therapeutics, Application > Consumer Products, TherapeuticArea > Oncology, Application > Medical Devices, Application > Non-Medical Devices, TherapeuticArea > Cardiology

Controlled Expression and Assembly of Human Group-C Rotavirus-like Particles for Creation of Rotavirus Diagnostic Assays and Improved Vaccine Formulations

CDC researchers have developed methods of producing unlimited quantities of Group-C (GpC) rotavirus antigens. GpC rotaviruses are a major, worldwide cause of acute gastroenteritis in children and adults that is distinct from Group-A rotavirus. However, GpC rotaviruses cannot be grown in culture, resulting in a lack of tools for detection and treatment...

Published: 7/25/2024 | Inventor(s): Baoming Jiang

Keywords(s): C, CDC Docket Import, CDC Docket Import CDC Prosecuting, CHILDHOOD, Children, DA4BXX, DA4XXX, DAXXXX, DB4BXX, DB4XXX, DBXXXX, DC1XXX, DC5BXX, DC5XXX, DCXXXX, DXXXXX, GROUP, Human, NEONATAL, Neonates, OID-NCIRD-DVD, PARTICLES, rotavirus, Their, THEREOF, viral, Viral-Like, virus, VLXXXX, VOXXXX, VPXXXX, WBXXXX, WFXXXX, WIXXXX, WMXXXX, XAXXXX, XCXXXX, YBXXXX

Category(s): Collaboration Sought > Licensing, TherapeuticArea > Immunology, ResearchProducts > Antibodies, TherapeuticArea > Cardiology, Application > Research Materials, Application > Occupational Safety and Health, Application > Vaccines, TherapeuticArea > Endocrinology, Application > Diagnostics, TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Oncology, Application > Consumer Products, TherapeuticArea > Dental